Quality Technical and Validation Lead

GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines.

Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges.

The Role:

The Quality Technical and Validation Lead ensures GxP compliance in validating and qualifying processes, equipment, facilities, utilities, software, and systems across manufacturing and analytical areas. It oversees new product introductions (NPI) and supports associated manufacturing and analytical activities to enable smooth product transfers between supply nodes. Responsibilities include maintaining robust change management for process, equipment, and computer system validation lifecycle activities, applying Quality by Design (QbD) principles, and ensuring adherence to GSK and regulatory standards for maintenance, validation, and product/process lifecycle management. The Quality Technical and Validation Manager reports to the Site Quality Director and is a member of the Quality Leadership Team (QLT).

Key Responsibilities

• GxP (Good Practice) Oversight of Validation and Qualification Activities. Ensure compliance with Good Manufacturing Practices (GMP) and other regulatory guidelines in the validation and qualification of processes, equipment, software, utilities and facilities.

• Manage the development and implementation of a validation maintenance program which periodically reviews the status of validated systems and ensures their adherence, for the production and laboratory value streams

• New Product Introduction (NPI): Provide quality oversight and approval of technology transfer activities to ensure adherence with GSK and regulatory standards. This includes review and approval of process and analytical tech transfer tasks, procedures and protocols.

• Work with enterprise partners (Research & Development (R&D), global MSAT (Manufacturing Science and Technology) /validation, Product Quality Leads) in identifying, evaluating and initiating strategies to rapidly develop product transfers by developing a partnership with the business areas to which they are aligned.

• Review and approve validation protocols for facility services, utilities, equipment, software, and laboratory systems; lead the validation team in supporting computer system validation and data integrity requirements.

• Oversee the cleaning validation program, including the master plan and ongoing validation maintenance.

• Assess, review, and approve change control activities related to validation and qualification.

• Ensure laboratory business applications and automation continue to meet testing and production needs during system changes.

• Support Pre‑Approval Inspections (PAI) and routine regulatory inspections as a topic lead or host.

• Provide Quality oversight for GxP engineering activities, including facilities, utilities, maintenance, and local product/process robustness investigations.

Why You!

Basic Qualifications

• Bachelor’s degree in Chemistry, Biology, engineering, or a related discipline.

• Experience in the pharmaceutical industry.

• Experience in Process Lifecycle Management activities.

• Experience working for quality operations.

• Experience using analytical equipment and performing method validation.

• Experience applying cGMP regulations, including process validation and product characterization guidelines.

• Experience applying leadership expectations by setting team priorities, coordinating workflow to maintain focus, carrying out defined development activities such as coaching or feedback sessions, practicing self‑awareness in daily interactions, and using agile and culturally adaptable approaches when managing tasks or projects. (Team size 8-10)

• Experience in performing analytical validation and transfer.

Preferred Qualifications

• GPS (GSK Production System) training or equivalent preferred

• Must be able to interact well with peers, subordinates, and senior personnel in multidisciplinary teams involving scientific, engineering, regulatory, and operational disciplines.

• Capable of providing direct supervision in a team-oriented atmosphere.

• Experience in communication, presentation, report writing, influencing, listening, and networking.

• Experience applying initiative in problem solving and troubleshooting.

• Knowledge of site business drivers.

• Experience influencing others, supporting collaboration, and contributing to change and innovation.

How to Apply:

If this role speaks to your experience and ambitions, please apply now. Share your CV and a short note explaining how your skills match this role and what impact you hope to make. We welcome applicants from all backgrounds and are happy to discuss reasonable adjustments to support you through the selection process.

Closing Date: 19th April 2026

Work Arrangements:

This role offers an on-site (weekly 5 days) working model at Ware, Hertfordshire, UK. Remote or fully home-working arrangements are not available for this role.

#LI-GSK

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

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